Introduction[ edit ] Heparan Sulfate molecules are found on the surface of the extracellular matrix of most animal tissues. It occurs as a proteoglycan HSPG in which two or three HS chains are attached in close proximity to cell surface or extracellular matrix proteins.
Bonnie Bassler loves her life as a biologist scrutinizing the secret lives of bacteria. For the past 20 years or so, Bonnie and her lab her gang, as she calls them have made momentous discoveries about how bacterial cells use chemicals to communicate with each other in a process called quorum sensing.
Bassler has a B. Among her many awards and honors, she has received a MacArthur Foundation Fellowship and is a member of the National Academy of Sciences. She is the President of the American Society for Microbiology, the largest specialized life science organization in the world.
How did you get started in science? I ve always been interested in nature and animals, and in puzzles and mystery books I really like guring things out. As an undergraduate at UC Davis, I worked in a lab on a bacterial project while taking courses in both biochemistry and genetics. Then, as a graduate student at Johns Hopkins, I learned a lot of biochemistry while studying marine bacteria.
The bacteria belong to the genus Vibrio, and I was working on chemotaxis, movement by cells toward food or away from noxious chemicals in the environment. What are the advantages of using bacteria for research in cell biology?
Bacteria have been the foundation of molecular biology for the last years because they re accessible. They grow fast, they form clones of identical cells, and they re amenable to biochemical and genetic analyses. Most of what we initially learned about molecular biology about genes and proteins and other biomolecules came from work done on bacteria.
Because of evolutionary history, the most basic and ancient life processes that happen in bacteria also happen in humans and other higher organisms. Mike had been working on a lightproducing bioluminescent marine bacterium called Vibrio scheri that lives symbiotically inside a variety of marine animals.
The animal provides nutrients for the bacteria, which live in an enclosed space within the animal s body. In return, the bacteria provide light that bene ts the animal by scaring away predators or attracting prey or a mate.
But if only a small number of bacteria are present, they do not make light producing light would waste energy because the light wouldn t be visible.
The word quorum means the number needed to do something, and bacteria can sense whether there is a quorum or not and act accordingly. The way quorum sensing works is that bacteria release certain signaling chemicals into the environment In a living system, diffusion involves a cell membrane.
Cells also need to excrete waste which also occurs at the cell membrane. This will be measured by the time it takes for the agar to become colourless. Research Question: How will changing the shape or size of the agar prisms affect the time taken for the sulfuric acid to diffuse into the centre?Introduction .
Heparan Sulfate molecules are found on the surface of the extracellular matrix of most animal tissues. It occurs as a proteoglycan (HSPG) in which two or three HS chains are attached in close proximity to cell surface or extracellular matrix proteins.
Jul 14, · Cell Shape and Diffusion-Practical Report (Re-Written) Year 11 IB Biology Title: Cell Shape and Diffusion Diffusion is a type of passive transport which allows particles to move from a region of high concentration to a region of low concentration.
In a living system, diffusion involves a cell membrane. Cells also need to excrete waste which also occurs at the cell membrane.
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